V. Mechanism of cathartic effect. J Okla.Dent.Assoc 2002;92(3):40-43. II. Odontology. Phytother Res 1993;7:S37-S42. Sahebnasagh A, Ghasemi A, Akbari J, et al. Aloe vera extract 0.5% in hydrophilic cream versus aloe vera gel for the measurement of genital herpes in males. Huseini HF, Kianbakht S, Hajiaghaee R, et al. Ai.Zheng. 2005;19:326-31. Gallagher J, Gray M. Is aloe vera effective for healing chronic wounds? View abstract. Those words truly describe the Cape Aloe Bitter Crystals from The House of Aloes in South Africa. B. 2020;108(3):470-478. Phytomedicine 2000;7(3):209-219. "Water pills" can also decrease potassium in the body. J Clin Pharm Ther. Swelling (inflammation) of the liver (hepatitis). Some stimulant laxatives include bisacodyl (Correctol, Dulcolax), cascara, castor oil (Purge), senna (Senokot), and others. Puataweepong P, Dhanachai M Dangprasert S Sithatani C Sawangsilp T Narkwong L et al. View abstract. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96. Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. View abstract. Effect of a dentifrice containing Aloe vera on plaque and gingivitis control. Ghannam, N., Kingston, M., Al Meshaal, I. View abstract. Early research shows that applying aloe to the skin might help skin survive frostbite injury. The stimulation of postdermabrasion wound healing with stabilized aloe vera gel-polyethylene oxide dressing. Itchy skin infection caused by mites (scabies). J Burn Care Rehabil 1988;9:156-9. View abstract. Oral Surg Oral Med Oral Pathol Oral Radiol 2013;116(6):717-24. Eur J Int Med 2006;17:589. Journal of the European Academy of Dermatology & Venerology 1996;7:294-95. Medications for diabetes (Antidiabetes drugs) interacts with ALOE. 2010;4(6):367-377. Olsen DL, Raub W, Bradley C, et al. Thongprasom K, Carrozzo M, Furness S, et al. Early research in people with oral submucous fibrosis shows that applying aloe gel reduces burning. 1976;14 Suppl 1:73-7. View abstract. View abstract. Kamath NP, Tandon S, Nayak R, Naidu S, Anand PS, Kamath YS. There has been 1 report that aloe gel as standard wound therapy delayed healing. A case of acute liver damage after aloe vera ingestion has been reported. Efficacy of Aloe vera/olive oil cream versus betamethasone cream for chronic skin lesions following sulfur mustard exposure: a randomized double-blind clinical trial. View abstract. The effects of aloe vera cream on split-thickness skin graft donor site management: a randomized, blinded, placebo-controlled study. View abstract. 1980;116(9):1064-1065. Int J Toxicol 2007;26 Suppl 2:1-50. Am J Roentgenol 1935;33(3):396-397. If you take warfarin, do not to take excessive amounts of aloe latex. View abstract. Am J Kidney Dis. View abstract. View abstract. J Clin Epidemiol 1997;50(suppl 1):3S. View abstract. The effect of aloe gel/mild soap versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy. Luyckx VA, Ballantine R, Claeys M, et al. J Med Food 2004;7:61-6. Collins CE. Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. The aloe cream was used along with a sitz bath three times daily, laxatives, and eating a full fiber diet. View abstract. Lee, T. and Dugoua, J. J. Nutritional supplements and their effect on glucose control. Arch Dermatol. 2003;31:40-2. J Ethnopharmacol. Precautions: Long term use of Aloe as a laxative can deplete the body of potassium, and low levels of potassium can cause dangerous irregularities of heart beats. J Derm Treatment 1997;8(2):99-102. Puvabanditsin P, Vongtongsri R. Efficacy of aloe vera cream in prevention and treatment of sunburn and suntan. Richardson, J., Smith, J. E., McIntyre, M., Thomas, R., and Pilkington, K. Aloe vera for preventing radiation-induced skin reactions: a systematic literature review. Herbal remedy-associated acute renal failure secondary to Cape aloes. Schorkhuber M, Richter M, Dutter A, et al. Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin. Acemannan hydrogel dressing versus saline dressing for pressure ulcers. View abstract. Melanoma Res 2005;15(6):489-494. Teplicki E, Ma Q, Castillo DE, et al. Klein AD, Penneys NS. View abstract. A randomised study of an Aloe vera derivative gel dressing versus conventional treatment after shave biopsy excisions. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. View abstract. 2011;10(12):1455-1461. Heggers, J. P., Kucukcelebi, A., Listengarten, D., Stabenau, J., Ko, F., Broemeling, L. D., Robson, M. C., and Winters, W. D. Beneficial effect of Aloe on wound healing in an excisional wound model. Esua, M. F. and Rauwald, J. W. Novel bioactive maloyl glucans from aloe vera gel: isolation, structure elucidation and in vitro bioassays. Hayes, S. M. Lichen planus--report of successful treatment with aloe vera. View abstract. Kaufman T, Kalderon N, Ullmann Y, Berger J. Aloe vera gel hindered wound healing of experimental second-degree burns: a quantitative controlled study. 2004 Sep 1;60:171-7. 2013 May;19(5):425-8. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. Morales-Bozo, I., Rojas, G., Ortega-Pinto, A., Espinoza, I., Soto, L., Plaza, A., Lozano, C., and Urzua, B. Najafian Y, Mazloum Z, Najaf Najafi M, Hamedi S, Mahjour M, Feyzabadi Z. Efficacy of Aloe vera/ Plantago major gel in diabetic foot ulcer: a randomized double-blind clinical trial. 2013 May;19(5):425-8. There is not enough research on the use of supplements containing cape aloe during pregnancy and breast-feeding, so consult a licensed healthcare practitioner before use or avoid use. 2018 Jan 14. doi: 10.2174/1570163815666180115093007. Int J Radiat Oncol Biol Phys 1996;36:345-9. Water pills (Diuretic drugs) interacts with ALOE. Some research shows that applying a gel containing aloe to the gums after getting dental appliances helps to prevent mouth sores. The efficacy of oral Aloe vera for radiation induced mucositis in head and neck cancer patients: a double-blind placebo controlled study. Journal of Clinical Epidemiology 1996;49(Suppl 1):24. Suksombon N, Poolsup N, Punthanitisarn S. Effect of aloe vera on glycaemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis. View abstract. Lin, J. G., Chen, G. W., Li, T. M., Chouh, S. T., Tan, T. W., and Chung, J. G. Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway. J Acquir Immune Defic Syndr Hum Retrovirol. A placebo-controlled, double-blind, comparative study. View abstract. Int J Dermatol. Gut 2000;46:651-5. Stimulant laxatives speed up the bowels. J Eur Acad Dermatol Venereol. View abstract. Early research suggests that applying a cream containing aloe extract to the skin for 2 weeks increases the amount of water in the outermost layer of the skin. Syed TA, Cheema KM, and Ahmad SA et al. Fogleman, R. W., Chapdelaine, J. M., Carpenter, R. H., and McAnalley, B. H. Toxicologic evaluation of injectable acemannan in the mouse, rat and dog. Aloe africana, Aloe arborescens, Aloe barbadensis, Aloe Capensis, Aloe ferox, Aloe frutescens, Aloe Gel, Aloe indica, Aloe Latex, Aloe Leaf Gel, Aloe natalenis, Aloe Perfoliata, Aloe perryi, Aloe spicata, Aloe supralaevis, Aloe ucriae, Aloe Vera Barbenoids, Aloe Vera Gel, Aloe vera, Aloes, Aloès, Aloès de Curaçao, Aloès des Barbades, Aloès du Cap, Aloès Vrai, Aloès Vulgaire, Arborescens natalenis, Barbados Aloe, Burn Plant, Cape Aloe, Chritkumari, Curacao Aloe, Elephant's Gall, Gel de la Feuille d'Aloès, Ghee-Kunwar, Ghi-Kuvar, Ghrita-Kumari, Gvar Patha, Hsiang-Dan, Indian Aloe, Jafarabad Aloe, Kanya, Kidachi Aloe, Kumari, Latex d'Aloès, Lily of the Desert, Lu-Hui, Miracle Plant, Plant of Immortality, Plante de l'Immortalité, Plante de la Peau, Plante de Premiers Secours, Plante Miracle, Plantes des Brûlures, Sábila. Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. View abstract. Comparison of alvogyl, SaliCept patch, and low-level laser therapy in the management of alveolar osteitis.J Oral Maxillofac Surg. Wounds 1994;6:4. Evaluation of polymannoacetate (carrisyn) in the treatment of AIDS. View abstract. View abstract. View abstract. Other symptoms of IBS include cramping, abdominal pain, flatulence, and bloating. Planta Med. 2012;2:CD008762. World J Gastroenterol 2005;11:303-4. Other side effects include abdominal cramps and diarrhea. Alkhouli M, Laflouf M, Alhaddad M. Efficacy of Aloe-vera use for prevention of chemotherapy-induced oral mucositis in children with acute lymphoblastic leukemia: A randomized controlled clinical trial. Visuthikosol V, Chowchuen B, Sukwanarat Y, et al. Cancer Lett 7-28-2006;239(1):55-63. This survey is being conducted by the WebMD marketing sciences department. Zhang Y, Liu W, Liu D, Zhao T, Tian H. Efficacy of aloe vera supplementation on prediabetes and early non-treated diabetic patients: a systematic review and meta-analysis of randomized controlled trials. Muller MJ, Hollyoak MA, Moaveni Z, et al. View abstract. J Am Podiatr.Med Assoc 1994;84(12):614-621. As with other strong laxatives, oral aloe may cause electrolyte imbalance and dangerously low blood sugar and potassium levels. Side Effects of Aloe … All rights reserved. Evaluation of aloe vera gel gloves in the treatment of dry skin associated with occupational exposure. But it doesn't seem to reduce the number of stretch marks. J Derm Treatment 1999;10:7-11. Br J Dermatol 2008;158(3):573-577. A double-blind clinical study in humans. Honig J, Geck P, and Rauwald HW. Taking 1 gram a day of aloe latex for several days can cause acute kidney failure and can be fatal. Journal of the European Academy of Dermatology & Venerology 1996;7(3):294-295. 2011 Feb;23(2):44-8. 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